The First International Congress of Alcohol Abuse, 21-23 May 2014, Addiction Research Center, Mashhad University of Medical Sciences, Mashhad, Iran , 2014-05-21

Title : ( Antioxidant Effect of Ardeh and Honey Combination on Ethanol-induced Oxidative stress in Liver and Kidney of Rats )

Authors: MAHMOUD EBRAHIMI1 , MOHSEN EBRAHIMI2 , ABOLGHASEM ALLAHYARI3 , Mostafa Gholizadeh , MOHAMMAD KARIMI5 , MOHAMMAD REZA KAZEMI5 , MARZIYEH KARIMI6 ,

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Abstract

Background: The pathogenesis of ethanol in the liver and kidney is associated with an increase in free radicals and oxidative stress that leads to structural and functional abnormalities in these vital organs. Methods: Forty-eight male wistar rats were placed in eight groups and were treated as follows: control group (normal saline), group of ethanol (4 g/ kg), three doses of Ardeh and honey combination (1, 2 and 5 g/ kg body weight), and the three groups received three doses of Ardeh and honey combination with ethanol (the same three doses of combinations along with 4 g/ kg ethanol). All treatments were performed once daily for 60 consecutive days with method of stomach gavages. Serum, liver and kidney tissue samples were obtained in order to assess serum components, tissue antioxidant enzyme activities, and the level of thiobarbituric acid reactive substances (TBARS).

Keywords

Antioxidants; Ethanol; Kidney; Liver; Oxidative Stress
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@inproceedings{paperid:1061758,
author = {MAHMOUD EBRAHIMI1 and MOHSEN EBRAHIMI2 and ABOLGHASEM ALLAHYARI3 and Gholizadeh, Mostafa and MOHAMMAD KARIMI5 and MOHAMMAD REZA KAZEMI5 and MARZIYEH KARIMI6},
title = {Antioxidant Effect of Ardeh and Honey Combination on Ethanol-induced Oxidative stress in Liver and Kidney of Rats},
booktitle = {The First International Congress of Alcohol Abuse, 21-23 May 2014, Addiction Research Center, Mashhad University of Medical Sciences, Mashhad, Iran},
year = {2014},
location = {مشهد, IRAN},
keywords = {Antioxidants; Ethanol; Kidney; Liver; Oxidative Stress},
}

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%0 Conference Proceedings
%T Antioxidant Effect of Ardeh and Honey Combination on Ethanol-induced Oxidative stress in Liver and Kidney of Rats
%A MAHMOUD EBRAHIMI1
%A MOHSEN EBRAHIMI2
%A ABOLGHASEM ALLAHYARI3
%A Gholizadeh, Mostafa
%A MOHAMMAD KARIMI5
%A MOHAMMAD REZA KAZEMI5
%A MARZIYEH KARIMI6
%J The First International Congress of Alcohol Abuse, 21-23 May 2014, Addiction Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
%D 2014

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