@inproceedings{paperid:1035431, author = {Eshghi, Hossein and Rahimizadeh, Mohammad and Kh. Abnous and Saberi, Satar}, title = {Synthesis of some novel 1,3,4-thiadiazine containing tetrazolonucleus}, booktitle = {20th Iranian Seminar of Organic Chemistry}, year = {2013}, location = {همدان, IRAN}, keywords = {1;3;4-Thiadiazines represent the most widely studied class of compounds among the six theoretically possible thiadiazine isomers; they are of interest in a chemical sense because they are labile compounds which are capable of undergoing intramolecular rearrangements to give thiazole and pyrazole derivatives. Moreover; 1;3;4-thiadiazinesexhibit a broad spectrum of biological activity 1 .In addition; tetrazole derivatives have been attracting attention due to their diverse pharmacological properties. For example; Angiotensin II receptor blockers such as losartan 2 and candesartan 3 ; contain tetrazole ring.In this study we described the synthesis of six novel Tetrazolo[5;1-b][1;3;4]Thiadiazines(5a–f) and (6a-f) wherein the biologically active 1;3;4-thiadiazine moiety is fused to a potent tetrazol ring across the 2;3-positions (Scheme 1).}, }