@inproceedings{paperid:1035444,
author = {Bakavoli, Mehdi and Eshghi, Hossein and Saberi, Satar and Azizolahy, Hamid},
title = {Synthesis of new derivatives of 2-Substitueted 4-(4-methyl-12Hpyrimido[4,5:5,6][1,4]thiazino[2,3-b]quinoxalin-2-yl)},
booktitle = {20th Iranian Seminar of Organic Chemistry},
year = {2013},
location = {همدان, IRAN},
keywords = {Nitrogen-containing heterocycles are undoubtedly one of the most important targets in organic chemistry. They are widely distributed in natural products and in pharmaceutical agents; and numerous studies for their chemistry and synthesis have been reported. 
Thiazinoquinoxaline derivatives are an important class of heterocyclic compounds that exhibit a broad spectrum of biological activities such as  antifungal; antibacterial; antimicrobial; antihypertensive[1;2];antiinflammatory[3]; calcium antagonistic; vasopressin receptor antagonistic [4]; and anticancer activityes [5]. These compounds are also calcium channel blockers and Na/H exchange inhibitoragents [6]. 
In this study we have described the synthesis of six novel of2-substitueted 4-(4-methyl-12Hpyrimido[4\\\\\\\';5\\\\\\\':5;6][1;4]thiazino[2;3-b]quinoxalin-2-yl) (3a–f) wherein the biologically active thiazinoquinoxalinemoiety is fused to a potent pyrimidine ring across the 2;3-positions (Scheme 1).},
}