Title : ( Iodine catalysed synthesis and antibacterial evaluation of thieno-[2,3-d]pyrimidine derivatives )
Authors: Mehdi Bakavoli , Gh. Bagherzadeh , M. Vaseghifar , Ali Shiri , Parvaneh Pordeli ,
Full TextAbstract
A new route via iodine catalysed heterocyclisation of 2-amino-4,5-dimethylthiophene-3-carboxamide with aromatic aldehydes affording a series of thieno[2,3-d]pyrimidine derivatives in a single step have been developed. Some of these compounds exhibited antibacterial activities comparable to Streptomycin as reference drug.
Keywords
, thieno[2, 3-d]pyrimidine, iodine, heterocyclisation, antibacterial evaluation, oxidative catalyst
@article{paperid:1013078,
author = {Bakavoli, Mehdi and Gh. Bagherzadeh and M. Vaseghifar and Shiri, Ali and Pordeli, Parvaneh},
title = {Iodine catalysed synthesis and antibacterial evaluation of thieno-[2,3-d]pyrimidine derivatives},
journal = {Journal of Chemical Research},
year = {2009},
number = {9},
month = {September},
issn = {1747-5198},
pages = {653--655},
numpages = {2},
keywords = {thieno[2;3-d]pyrimidine; iodine; heterocyclisation; antibacterial evaluation; oxidative catalyst},
}
%0 Journal Article
%T Iodine catalysed synthesis and antibacterial evaluation of thieno-[2,3-d]pyrimidine derivatives
%A Bakavoli, Mehdi
%A Gh. Bagherzadeh
%A M. Vaseghifar
%A Shiri, Ali
%A Pordeli, Parvaneh
%J Journal of Chemical Research
%@ 1747-5198
%D 2009
