Title : ( Molecular iodine promoted synthesis of new pyrazolo[3,4-d] pyrimidine derivatives as potential antibacterial agents )
Authors: Mehdi Bakavoli , Ghodsieh Bagherzadeh , Maryam Vaseghifar , Ali Shiri , Mehdi Pordel , Mansour Mashreghi , Parvaneh Pordeli , maryam sadat araghi shahri ,
Full TextAbstract
Iodocyclization of 5-amino-1-(2,4-dinitrophenyl)-1H-4-pyrazolcarboxamides with aromatic aldehydes gave a new series of pyrazolo[3,4-d]pyrimidine derivatives in a single step and their antibacterial activity comparable to Streptomycin as reference drug was evaluated.
Keywords
, Pyrazolo[3, 4-d] pyrimidine, Antibacterial agents, Iodine, Heterocyclization
@article{paperid:1013694,
author = {Bakavoli, Mehdi and Ghodsieh Bagherzadeh and Maryam Vaseghifar and Shiri, Ali and Pordel, Mehdi and Mashreghi, Mansour and Pordeli, Parvaneh and Araghi Shahri, Maryam Sadat},
title = {Molecular iodine promoted synthesis of new pyrazolo[3,4-d] pyrimidine derivatives as potential antibacterial agents},
journal = {European Journal of Medicinal Chemistry},
year = {2010},
volume = {45},
number = {2},
month = {February},
issn = {0223-5234},
pages = {647--650},
numpages = {3},
keywords = {Pyrazolo[3;4-d] pyrimidine; Antibacterial agents; Iodine; Heterocyclization},
}
%0 Journal Article
%T Molecular iodine promoted synthesis of new pyrazolo[3,4-d] pyrimidine derivatives as potential antibacterial agents
%A Bakavoli, Mehdi
%A Ghodsieh Bagherzadeh
%A Maryam Vaseghifar
%A Shiri, Ali
%A Pordel, Mehdi
%A Mashreghi, Mansour
%A Pordeli, Parvaneh
%A Araghi Shahri, Maryam Sadat
%J European Journal of Medicinal Chemistry
%@ 0223-5234
%D 2010
