Veterinary Research Communications, ( ISI ), Volume (27), No (1), Year (2003-1) , Pages (53-62)

Title : ( Experimental Tribulus terrestris poisoning in sheep: clinical, laboratory and pathological findings )

Authors: Mohammad Reza Aslani , Ahmad Reza Movassaghi , Mehrdad Mohri , M. Pedram , Abbas Parham ,

Citation: BibTeX | EndNote

Eleven native sheep, 1-2 years old, of both sexes were randomly divided into two groups, 6 sheep being allocated to the experimental group and 5 serving as controls. The sheep in the experimental group were fed 80% Tribulus terrestris and 20% alfalfa hay and wheat straw, while the control sheep were given a mixture of 40% alfalfa hay and 60% wheat straw. Clinical signs of hepatogenous photosensitivity were observed from day 11, including reddening and crust formation on the muzzle, nose, ears and eyelids, depression, weight loss, icterus, conjunctivitis, and yellow discoloration of the urine. Laboratory findings on weekly samples indicated significant differences (p < 0.05) in white blood cell count, total plasma protein and fibrinogen, total and direct bilirubin, blood urea nitrogen and creatinine concentrations, and aspartate aminotransferase and alkaline phosphatase activities. There were no significant differences in the packed cell volume, in the neutrophil, lymphocyte or eosinophil counts, or in the serum calcium, phosphorus, potassium, sodium or chloride concentrations. At necropsy of the experimental animals, there were various degrees of generalized icterus and the livers were swollen and discolored by bile pigment. Histopathological examination revealed varying amounts of crystalloid material in the bile ducts and renal tubules, hepatocellular degeneration, biliary fibrosis and proliferation, renal tubular necrosis and focal necrosis of cardiac muscle

Keywords

, Alakline phophatase, Sheep, tribulus
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@article{paperid:1014160,
author = {Aslani, Mohammad Reza and Movassaghi, Ahmad Reza and Mohri, Mehrdad and M. Pedram and Parham, Abbas},
title = {Experimental Tribulus terrestris poisoning in sheep: clinical, laboratory and pathological findings},
journal = {Veterinary Research Communications},
year = {2003},
volume = {27},
number = {1},
month = {January},
issn = {0165-7380},
pages = {53--62},
numpages = {9},
keywords = {Alakline phophatase; Sheep; tribulus terrestris;....},
}

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%0 Journal Article
%T Experimental Tribulus terrestris poisoning in sheep: clinical, laboratory and pathological findings
%A Aslani, Mohammad Reza
%A Movassaghi, Ahmad Reza
%A Mohri, Mehrdad
%A M. Pedram
%A Parham, Abbas
%J Veterinary Research Communications
%@ 0165-7380
%D 2003

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