Hemorrhagic bowel syndrome is a highly fatal intestinal disease of adult dairy cattle with uncertain cause. In a dairy herd in Khorasan Razavi province, Northeast of Iran, two cows showed depression, anorexia, decrease in milk production, ruminal hypomotility, bruxism and dehydration. At necropsy, massive hemorrhage and clot formation was observed within the jejunum and bacterial culture of the intestinal ingesta and lesions showed the presence of a large number of Clostridium perfringens. Subacute ruminal acidosis was detected in fresh and mid-lactation cows. This report shows the possibility of diagnosis of other hemorrhagic bowel syndrome cases in dairy cows in Iran

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