Wounds, ( ISI ), Volume (23), No (2), Year (2011-2) , Pages (38-43)

Title : ( Influence of Short-term, RepeatedFasting on the Skin Wound Healingof Female Mice )

Authors: Farzad Hayati , MOHSEN MALEKI , - - , Kamran Sardari , Mehrdad Mohri , Amir Afkhami Goli ,

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Caloric restriction in mice has been found to retard the rate of aging, increase mean and maximum life spans, and inhibit the occurrence of many age-associated diseases. The following study was conducted to investigate the effect of short-term repeated fasting (4 consecutive days, every 2 weeks) before wound creation on skin wound healing. Mice were used for macroscopic study (n = 40) and hydroxyproline analysis (n = 10). Mice were also used for microscopic study (n = 36) and were divided equally into a fasting group and a control group. The results revealed that there were significant differences in epithelialization, contraction, healing, amount of collagen, and hydroxyproline between the control and fasting groups (P < 0.05). Based on the results, it can be argued that caloric restriction preceding the wound-healing period has the potential to accelerate the healing process.

Keywords

, Dog, Wound, Fasting,
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@article{paperid:1021346,
author = {Hayati, Farzad and MALEKI, MOHSEN and -, - and Sardari, Kamran and Mohri, Mehrdad and Afkhami Goli, Amir},
title = {Influence of Short-term, RepeatedFasting on the Skin Wound Healingof Female Mice},
journal = {Wounds},
year = {2011},
volume = {23},
number = {2},
month = {February},
issn = {1044-7946},
pages = {38--43},
numpages = {5},
keywords = {Dog; Wound; Fasting; Mice},
}

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%0 Journal Article
%T Influence of Short-term, RepeatedFasting on the Skin Wound Healingof Female Mice
%A Hayati, Farzad
%A MALEKI, MOHSEN
%A -, -
%A Sardari, Kamran
%A Mohri, Mehrdad
%A Afkhami Goli, Amir
%J Wounds
%@ 1044-7946
%D 2011

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