This study is concerned with examining the differences in general English course achievement among university students of humanities, sciences, and engineering. It also explores the effect of self-efficacy in GE course achievement among these three groups of university students. The results of the study indicated that 1. There is a significantly positive relationship between the university students' self-efficacy and their achievement in GE course.2. There are significant differences in GE course achievement among the three groups of students, and 3. There are significant differences in self-efficacy among the three groups of university students. The results of teachers' interviews were also in agreement with those of the Iranian EFL Journal 154 questionnaires. The findings of this study can draw the attention of general English course teachers to the fact that encouraging their students to seek ways to improve their self-efficacy can be really helpful for them to achieve higher scores in general English course.

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