Title : ( The healing effect of lavandula angustifolia hydroalcholic extract on the repair of indomethacin induced gastric ulcer in rats )
Authors: shirin esmaeilian , Nasser Mahdavi SHahri , Masoud Fereidoni , H. Rakhshandeh , S. Niazmand , Esmat Saadatiyan ,
Full TextAbstract
Objectives: To determine the healing effect of lavandulaan gustifolia in indomethacin-induced gastric ulcer in rats. Materials & Methods: Male Wistar rats (250-300g) divided randomly into five groups (n=6). Including control, indomethacin solvent, indomethacin (50mg/kg) in 1% carboxy methyl cellulose orally induced gastric ulcer and two gastric ulcer, 3days orally treating groups, by lavandulaan gustifolia hydroalcholic extract (200&300mg/kg). In the 3th day, rats were sacrificed .Number and length of ulcers calculated under the stereomicroscope and the ulcer index and curative ratio were calculated. Result: The L.angustifolia extract significantly decreased the gastric ulcer indexs in comparison with control and indomethacin groups (P<0.01). A significant difference in the inflammatory and repair parameters during the healing process between treated and nontreated cases. Conclusions: The results suggest that L.angustifolia hydroalcolic extract can exert significant mucosal layer protection.
Keywords
, lavandula angustifolia, Gastric ulcer, Indomethacin, Ulcer index, Rat.
@inproceedings{paperid:1034240,
author = {Esmaeilian, Shirin and Mahdavi SHahri, Nasser and Fereidoni, Masoud and H. Rakhshandeh and S. Niazmand and Saadatiyan, Esmat},
title = {The healing effect of lavandula angustifolia hydroalcholic extract on the repair of indomethacin induced gastric ulcer in rats},
booktitle = {13th Iranian Congress of Biochemistry and 5th International Congress of Biochemistry and Molecular Biology},
year = {2013},
location = {یزد, IRAN},
keywords = {lavandula angustifolia; Gastric ulcer; Indomethacin; Ulcer index; Rat.},
}
%0 Conference Proceedings
%T The healing effect of lavandula angustifolia hydroalcholic extract on the repair of indomethacin induced gastric ulcer in rats
%A Esmaeilian, Shirin
%A Mahdavi SHahri, Nasser
%A Fereidoni, Masoud
%A H. Rakhshandeh
%A S. Niazmand
%A Saadatiyan, Esmat
%J 13th Iranian Congress of Biochemistry and 5th International Congress of Biochemistry and Molecular Biology
%D 2013
