Title : ( Investigation of nano-SiO2 impact on mechanical and biocompatibility properties of cyanoacryalate based nanocomposites for dental application )
Authors: Sima Afsharnezhad , Mehrdad Kashefi Torbati , Javad Behravan , Melika Ehtesham Gharaee , Mojtaba Meshkat , Khadijeh Shahrokh Abadi , Masoud Homayoni Tabrizi ,
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Abstract
Although cyanoacrylate glues are widelyused inmedicine,cyanoacrylate-based nanocomposites have been recently suggested for dental restorative/filling applications.In the present research,SiO2 nanoparticles were usedas filler for development of a novel dental nanocomposite base on alkoxy- ethyl-cyanoacrylate.The mechanical properties of nanocomposite samples filled with different levels of nano-sized SiO2 (wt%) were evaluated and comparisons were made with the neat cyanoacrylate.The hardness and wear behavior of the samples were measured using Vickers hardness and pin-on-disk tester,respectively.The wear mechanism of the samples was alsoe valuated using scanning electron microscopy(SEM).Furthermore,cell biocompatibility of the samples using MTTandL DH assays as well as inflammatory cytokine expression interleukin-6(IL-6) from L929 cells was investigated.The results showed that anincrease in nano-sizedSiO2 content improves hardness and wear resistance of the cyanoacrylate-based nanocomposites and changes the wear mechanism from adhesive to abrasive.The results of cytotoxicity analysis showed a significant reduction in cell viability and IL-6 produced from the samples-exposed L929 cells compared with untreated control cells. Moreover, increasing the nano SiO2 powder content caused a decrease in ther eleased formaldehyde.
Keywords
, Cyanoacrylate, Nano-sized SiO2, Nanocomposite, Biocompatibility, Mechanical properties
@article{paperid:1042510,
author = {Sima Afsharnezhad and Kashefi Torbati, Mehrdad and Javad Behravan and Melika Ehtesham Gharaee and Mojtaba Meshkat and Khadijeh Shahrokh Abadi and Masoud Homayoni Tabrizi},
title = {Investigation of nano-SiO2 impact on mechanical and biocompatibility properties of cyanoacryalate based nanocomposites for dental application},
journal = {International Journal of Adhesion and Adhesives},
year = {2014},
number = {54},
month = {October},
issn = {0143-7496},
pages = {177--183},
numpages = {6},
keywords = {Cyanoacrylate; Nano-sized SiO2; Nanocomposite; Biocompatibility; Mechanical properties},
}
%0 Journal Article
%T Investigation of nano-SiO2 impact on mechanical and biocompatibility properties of cyanoacryalate based nanocomposites for dental application
%A Sima Afsharnezhad
%A Kashefi Torbati, Mehrdad
%A Javad Behravan
%A Melika Ehtesham Gharaee
%A Mojtaba Meshkat
%A Khadijeh Shahrokh Abadi
%A Masoud Homayoni Tabrizi
%J International Journal of Adhesion and Adhesives
%@ 0143-7496
%D 2014
