Chromosome,doubling used اn several plants mainly with the aim of providing superior plant genomes for breeding purposes. Secondary metabolite production in plants is highly alterd by genome evolution. This modificatior of secondary metaboite content in plant could increase plant resistance against pathogens or may increase concenlration of them to levels that are poisonous for human consumprion. The objective of the currenl study was lo investigate thc effect of polyploidizalion on the glycoalkaloid cortenr of four Diploid and Tettploid eggplanl cultivars in the frame of a research program on examination of different ploidy levels on brinjal physiological and phonologhcal properties. Here we aimed to find if tetraploidy have any superiority despite diploid culnvars. We also want lo examine the alteration in glycoalkaloid conlent of eggplan make it harmful or more beneficial to humans results showed no superioty in any of tetraploid cultivars but cleared the changing trend of glycoalkaloid contenl in shoots and fruits of Solanum melongena during different growth phases

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