Title : ( Inhibition of quorum sensing in Pseudomonas aeruginosa by two herbal essential oils from Apiaceae family )
Authors: Ehsan Sepahi Karnave , Saeed Tarighi , Farajollah Shahriari Ahmadi , Abdolreza Bagheri ,
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Abstract
Ferula (Ferula asafoetida L.) and Dorema (Dorema aucheri Bioss.) both from Apiaceae family were tested for their anti-quorum sensing (QS) activity against Pseudomonas aeruginosa. Both essential oils exhibited anti-QS activity at 25 μg/ml of concenteration. At this concenteration Ferula fully abolished and Dorema reduced the violacein production by C. violaceum. Pyocyanin, pyoverdine, elastase and biofilm production were decreased in Ferula oil treatments. Dorema oil reduced pyoverdine and elastase production, while pyocyanin and biofilm production were not affacted. Expresion analysis of QS-dependent genes confirmed our phenotypic data. Our data introduced native Dorema and Ferula plants as novel QS and virulence inhibitors.
Keywords
, quorum sensing, N-acyl-homoserine lactones, Pseudomonas aeruginosa, Dorema aucheri, Ferula assafoetida, quorum quenching, virulence
@article{paperid:1047228,
author = {Sepahi Karnave, Ehsan and Tarighi, Saeed and Shahriari Ahmadi, Farajollah and Bagheri, Abdolreza},
title = {Inhibition of quorum sensing in Pseudomonas aeruginosa by two herbal essential oils from Apiaceae family},
journal = {Journal of Microbiology},
year = {2015},
volume = {53},
number = {2},
month = {February},
issn = {1225-8873},
pages = {176--180},
numpages = {4},
keywords = {quorum sensing; N-acyl-homoserine lactones; Pseudomonas aeruginosa; Dorema aucheri; Ferula assafoetida;
quorum quenching; virulence},
}
%0 Journal Article
%T Inhibition of quorum sensing in Pseudomonas aeruginosa by two herbal essential oils from Apiaceae family
%A Sepahi Karnave, Ehsan
%A Tarighi, Saeed
%A Shahriari Ahmadi, Farajollah
%A Bagheri, Abdolreza
%J Journal of Microbiology
%@ 1225-8873
%D 2015
