Introduction: The aim of this study was to investigate the evidence-based approach to customer-orientation care physicians in the province, them being the target group. Research method: This is a descriptive-analytical and cross-sectional design, which was performed in 2014. The statistical society in this study comprised 212 doctors in the health centers. The employed physicians selected 200 patients through a simple random sampling. The measurement tool was the researcher made questionnaire whose validity and reliability were confirmed. In this study, the structural equation modeling and partial least square method were used to test the assumptions and fitness model and the structural model was fit as acceptable. Findings: The results indicated four cases related to attitude, a behavior which was intended to treat; common sources of evidence were used to retrieve information according to the best evidence and the lack of barriers to the performance of customer orientation approach of evidence-based effects were significant. Two dimensions of the doctor’s knowledge, the lack of barriers, and the finding of the evidence of dimensions regarding the customer orientation approach were based on evidence that had no significant effect. Conclusion: The use of evidence-based education not only improved knowledge, attitude, and skills of the doctors, but also enabled them to respond to the needs of clients in making better decisions and providing a higher quality of care, by reducing treatment costs for patients, attracting patients’ satisfaction, and ultimately having a better efficacy for patients and organizations.

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