Tanaffos, Volume (17), No (4), Year (2018-10) , Pages (211-222)

Title : ( Protective Effects of Thymoquinon on Pulmonary Disorders in Experimental Studies )

Authors: Mohammad-Foad Noorbakhsh , Hanieh Shaterzadeh-Yazdi , Farzad Hayati , Saeed Samarghandian , Tahereh Farkhondeh ,

Access to full-text not allowed by authors

Citation: BibTeX | EndNote

Abstract

Lung as vital organ is exposed to many injurious agents that can cause inflammation and oxidative stress, which are potential causes in the pathogenesis of lung diseases. Nigella sativa, usually introduced as black seed, has been considered for treatment of various diseases and is one the most widely investigated herbs. Thymoquinone (TQ) is the major component of the volatile oil of black seed (54%) which has been indicated to anti-oxidant, anti-inflammatory and anti-neoplastic properties. There is interesting to study on TQ effect as a therapeutic agent for various diseases in both in vivo and in vitro conditions. In this comprehensive review, we summarized the recent studies related to the effectiveness of TQ on lung disorders such as inflammatory lung diseases, lung fibrosis, asthma and lung cancer. It is concluded that TQ with anti-inflammatory, anti- oxidant, anti-asthmatic and anti- tumor activity can provide therapeutic effects against lung disorders. However, more investigation is needed to produce TQ as a pharmaceutical preparation for human studies.

Keywords

, Thymoquinone, Lung inflammation, Asthma, Lung fibrosis, Lung cancer
برای دانلود از شناسه و رمز عبور پرتال پویا استفاده کنید.

@article{paperid:1082038,
author = {Mohammad-Foad Noorbakhsh and Hanieh Shaterzadeh-Yazdi and Hayati, Farzad and Saeed Samarghandian and Tahereh Farkhondeh},
title = {Protective Effects of Thymoquinon on Pulmonary Disorders in Experimental Studies},
journal = {Tanaffos},
year = {2018},
volume = {17},
number = {4},
month = {October},
issn = {1735-0344},
pages = {211--222},
numpages = {11},
keywords = {Thymoquinone; Lung inflammation; Asthma; Lung fibrosis; Lung cancer},
}

[Download]

%0 Journal Article
%T Protective Effects of Thymoquinon on Pulmonary Disorders in Experimental Studies
%A Mohammad-Foad Noorbakhsh
%A Hanieh Shaterzadeh-Yazdi
%A Hayati, Farzad
%A Saeed Samarghandian
%A Tahereh Farkhondeh
%J Tanaffos
%@ 1735-0344
%D 2018

[Download]