Title : ( Synthesis of novel trifluoro methylated imidazothiadiazole derivatives via one-pot isocyanide-based three-component reaction under catalyst and solvent-free conditions )
Authors: maryam sarchahi , Abbas Ali Esmaeili ,
Full TextAbstract
A catalyst and solvent-free synthesis of imidazo[2,1-b][1,3,4]thiadiazole derivatives containing one trifluoromethyl (CF3) group is reported via a three-component reaction between 5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine, aromatic aldehydes, and isocyanides. This green reaction is characterized by operational simplicity and good-to-excellent yields of products. The structure of all products was deduced by 1H NMR,13C NMR, FT-IR, mass spectrometry, and elemental analysis.
Keywords
, Multicomponent dominoreactions; imidazo[2, 1-b][1, 3, 4]thiadiazole; catalystfree isocyanide; solvent-free; green chemistry
@article{paperid:1086050,
author = {Sarchahi, Maryam and Esmaeili, Abbas Ali},
title = {Synthesis of novel trifluoro methylated imidazothiadiazole derivatives via one-pot isocyanide-based three-component reaction under catalyst and solvent-free conditions},
journal = {Phosphorus, Sulfur, and Silicon and the Related Elements},
year = {2021},
volume = {196},
number = {12},
month = {August},
issn = {1042-6507},
pages = {1071--1077},
numpages = {6},
keywords = {Multicomponent dominoreactions; imidazo[2;1-b][1;3;4]thiadiazole; catalystfree isocyanide; solvent-free;
green chemistry},
}
%0 Journal Article
%T Synthesis of novel trifluoro methylated imidazothiadiazole derivatives via one-pot isocyanide-based three-component reaction under catalyst and solvent-free conditions
%A Sarchahi, Maryam
%A Esmaeili, Abbas Ali
%J Phosphorus, Sulfur, and Silicon and the Related Elements
%@ 1042-6507
%D 2021
