Title : ( Application of Conventional and New Biotechnological Approaches for Improving of Morphinane Alkaloids Production )
Authors: esmail dehghan , B. Hosseini , H. Naghdi Badi , Farajollah Shahriari Ahmadi ,Abstract
More than 12,000 alkaloids are known in plants, mostly used as medicine with a world market value of about 4 billion US$. Opium poppy, Papaver somniferum, is the most important economic source of morphinane alkaloids such as morphine, codeine, thebaine, narcotine and papaverine that are exploited by the pharmaceutical industry as analgesics, antitussives and anti-spasmodics. With regard to increasing demand for these compounds, the aim of this review is presenting an outlook of classical breeding programs that successfully applied for enhancing the alkaloid content of opium poppy. The latest biotechnological approaches also are discussed to give an outlook for future trends and possibilitie
Keywords
, Papaver species, Biotechnological methods, Conventional breeding, Morphinane Alkaloids, Tissue culture, Metabolic engineering@article{paperid:1022071,
author = {Dehghan, Esmail and B. Hosseini and H. Naghdi Badi and Shahriari Ahmadi, Farajollah},
title = {Application of Conventional and New Biotechnological Approaches for Improving of Morphinane Alkaloids Production},
journal = {گیاهان دارویی- Journal of Medicinal Plants},
year = {2010},
volume = {9},
number = {3},
month = {June},
issn = {2717-204X},
pages = {33--50},
numpages = {17},
keywords = {Papaver species; Biotechnological methods; Conventional breeding; Morphinane
Alkaloids; Tissue culture; Metabolic engineering},
}
%0 Journal Article
%T Application of Conventional and New Biotechnological Approaches for Improving of Morphinane Alkaloids Production
%A Dehghan, Esmail
%A B. Hosseini
%A H. Naghdi Badi
%A Shahriari Ahmadi, Farajollah
%J گیاهان دارویی- Journal of Medicinal Plants
%@ 2717-204X
%D 2010