Title : ( Optimal Control of Bone Marrow in Cancer Chemotherapy )
Authors: mohammad hadi noori skandari , Hamid Reza Erfanian , Ali Vahidian Kamyad , S. Mohammadi ,Abstract
We introduce an optimal method for controlling the bone marrow dynamics in cell-cycle-specific cancer chemotherapy. This method is based on measure theory and gives us the strategy applying drug where both bone marrow mass and the dose be maximized over the treatment interval. Using measure theory, the corresponding optimal control problem be transfer into a modified problem which is a type of an infinite dimensional linear programming problem whose its optimal solution can be approximated by optimal solution of finite dimensional problem.
Keywords
, Optimal control, Cancer chemotherapy, Bone Marrow, Measure theory@article{paperid:1028481,
author = {Noori Skandari, Mohammad Hadi and Erfanian, Hamid Reza and Vahidian Kamyad, Ali and S. Mohammadi},
title = {Optimal Control of Bone Marrow in Cancer Chemotherapy},
journal = {European Journal of Experimental Biology},
year = {2012},
volume = {2},
number = {3},
month = {June},
issn = {2248-9215},
pages = {562--569},
numpages = {7},
keywords = {Optimal control; Cancer chemotherapy; Bone Marrow; Measure theory},
}
%0 Journal Article
%T Optimal Control of Bone Marrow in Cancer Chemotherapy
%A Noori Skandari, Mohammad Hadi
%A Erfanian, Hamid Reza
%A Vahidian Kamyad, Ali
%A S. Mohammadi
%J European Journal of Experimental Biology
%@ 2248-9215
%D 2012