This chapter explores the recondite layers of Langerian Mindfulness in psychology and indicates that Langerian Mindfulness calls for an ultimately psychological, ontological, and epistemological shift of paradigm. The chapter focuses on the implications of Mindfulness and its potential power in opening up the realm of psychology of possibility while elucidating how a mindful way of knowing in psychology may give rise to radical transformation of consciousness in numerous levels. Langerian psychology examines the foundational realm of thinking and knowing and demonstrates how mainstream psychology may have been subjected to psychological and ontological encapsulating approaches.