Title : A Facile Synthesis of (S)-(-)- Propranolol ( A Facile Synthesis of (S)-(-)- Propranolol )
Authors: Hossein Eshghi , H. Porkar Yazdi ,
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Abstract
A one-pot synthesis of (S)-(-)-propranolol is reported. Zn(NO3)2/(+)-tartaric acid catalyzed enantioselective synthesis of (S)-(-)-propranolol via kinetic resolution of key intermediate α-naphthyl glycidyl ether with high optical and chemical yield.
Keywords
Propranolol; Enantioselective synthesis; Kinetic resolution
@article{paperid:1005813,
author = {Eshghi, Hossein and H. Porkar Yazdi},
title = {A Facile Synthesis of (S)-(-)- Propranolol},
journal = {Journal of Sciences, Islamic Republic of Iran},
year = {2003},
volume = {14},
number = {1},
month = {January},
issn = {1016-1104},
pages = {17--19},
numpages = {2},
keywords = {Propranolol; Enantioselective synthesis; Kinetic resolution},
}
%0 Journal Article
%T A Facile Synthesis of (S)-(-)- Propranolol
%A Eshghi, Hossein
%A H. Porkar Yazdi
%J Journal of Sciences, Islamic Republic of Iran
%@ 1016-1104
%D 2003
