Present study was performed with the main goal of investigating the effect of existential group therapy on the promotion of mood in women after myocardial infarction (MI).Studies in two decades have presented relationship between depression, cardiovascular disease and mortality. The subjects were selected by using convenient sampling method from the list of women after MI. 24 subjects selected (12 persons in each group). Then the Beck Depression Inventory (BDI) with a reliability ratio of 0.86 was performed as pre-test and post-test. The experimental group was subjected to the intervention of existential group therapy. After a 12-session treatment (3 months, each session being tow hours) in excremental group in order to measure the dependant variable (depression), Beck Depression Inventory was performed as post-test. The results of statistical analysis of T-test supported the main hypothesis (verified with a significant value of p= 14% and reliability of 95%) and secondary hypothesis (verified with a significant value pf p= 01% and reliability of 95%). As a result, existential group therapy in comparison with control group would significantly reduce the amount of depression in women after MI. Keywords: existential, group therapy, depression, myocardial infarction

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