Title : ( The role of endogenous opioids in the protective effects of local sublethal hyperthermia against the progression of burn injury )
Authors: Neda Karimi , زهیر محمدحسن , Morteza Behnam Rassouli , بهروز ایلخانی زاده , شاکر سالاری لک , شهرام شهابی ,
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Abstract
The aim of the presents tudy was to evaluate the role of endogenous opioids in local sublethal hyperthermia-induced protection against burn injury. Second-degree burn wounds were induced on the back of Balb/c mice. Progression of burn injury and expression of heat shock protein(HSP)-70 were evaluated afte r24h. Both inhibition of HSP synthesis and blocking opioid receptors before applying local sublethal hyperthermia decreased the protective effects of sublethal hyperthermia against the progression of burn injury. Blocking opioid receptors attenuated induction of HSP-70 by sublethal hyperthermia..
Keywords
, Sublethal hyperthermia Thermotolerance Burn Endogenousopioids HSP, 70
@article{paperid:1012045,
author = {Karimi, Neda and زهیر محمدحسن and Behnam Rassouli, Morteza and بهروز ایلخانی زاده and شاکر سالاری لک and شهرام شهابی},
title = {The role of endogenous opioids in the protective effects of local sublethal hyperthermia against the progression of burn injury},
journal = {Journal of Thermal Biology},
year = {2009},
volume = {34},
number = {6},
month = {August},
issn = {0306-4565},
pages = {286--289},
numpages = {3},
keywords = {Sublethal hyperthermia
Thermotolerance
Burn
Endogenousopioids
HSP-70},
}
%0 Journal Article
%T The role of endogenous opioids in the protective effects of local sublethal hyperthermia against the progression of burn injury
%A Karimi, Neda
%A زهیر محمدحسن
%A Behnam Rassouli, Morteza
%A بهروز ایلخانی زاده
%A شاکر سالاری لک
%A شهرام شهابی
%J Journal of Thermal Biology
%@ 0306-4565
%D 2009
