Title : ( stereoselective Aminomethylation of m-Cresol with Chiral Amine Medioated by 4A Molecular ieves nder Neat Conditions )
Authors: Mostafa Gholizadeh ,
Full TextAbstract
Aminomethylation at ortho position was performed with respect to hydroxyl group of m-cresol in the presence of carefully dried 4Ao molecular sieves under neat conditions. One pot, two components, Mannich reaction of m-Cresol with imine at 60oC under Solvent-free conditions affords the corresponding aminomethylated products in good yields, with moderate stereoselectivity.
Keywords
, Aminomethylation , Mannich reaction, Solvent-free Conditions m-Cresol, Diastereoselectivity
@article{paperid:1014887,
author = {Gholizadeh, Mostafa},
title = {stereoselective Aminomethylation of m-Cresol with Chiral Amine Medioated by 4A Molecular ieves nder Neat Conditions},
journal = {The Open Catalysis Journal},
year = {2009},
volume = {2},
number = {1},
month = {January},
issn = {1876-214X},
pages = {30--36},
numpages = {6},
keywords = {Aminomethylation ; Mannich reaction; Solvent-free Conditions m-Cresol; Diastereoselectivity},
}
%0 Journal Article
%T stereoselective Aminomethylation of m-Cresol with Chiral Amine Medioated by 4A Molecular ieves nder Neat Conditions
%A Gholizadeh, Mostafa
%J The Open Catalysis Journal
%@ 1876-214X
%D 2009
