Title : ( Investigation into the Reaction of 2-Amino- 4,5-dimethylthiophene-3-carboxamide with Iso(and Isothio)cyanates under Microwave Irradiation )
Authors: Abolghasem Davoodnia , Mohammad Rahimizadeh , Hoda Atapour-Mashhad , Niloofar Tavakoli-Hoseini ,
Full TextAbstract
The reaction of 2-amino-4,5-dimethylthiophene-3-carboxamide with iso(and isothio) cyanates for the synthesis of thieno[2,3-d]pyrimidines has been investigated. The reactions under microwave irradiation in the presence of N,N-dimethyl acetamide as solvent gave 5,6-dimethylthieno[2,3-d]pyrimidine- 2,4(1H,3H) -dione, 5,6-dimethyl-2-thioxo-2,3-dihydrothieno[ 2,3-d]pyrimidin-4(1H)-one, and 2-arylamino- 5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one derivatives. These reactions probably proceed through intermediates 4,5-dimethyl-2-substitutedcarbamothioylaminothiophene-3-carboxamides. Two of these intermediates were isolated.
Keywords
, 2-Amino-4, 5-dimethylthiophene-3-carboxamide- Iso(and Isothio)cyanates- Microwave Irradiation
@article{paperid:1025387,
author = {Abolghasem Davoodnia and Rahimizadeh, Mohammad and Hoda Atapour-Mashhad and Niloofar Tavakoli-Hoseini},
title = {Investigation into the Reaction of 2-Amino- 4,5-dimethylthiophene-3-carboxamide with Iso(and Isothio)cyanates under Microwave Irradiation},
journal = {Heteroatom Chemistry},
year = {2009},
volume = {20},
number = {6},
month = {June},
issn = {1042-7163},
pages = {346--349},
numpages = {3},
keywords = {2-Amino-4;5-dimethylthiophene-3-carboxamide- Iso(and Isothio)cyanates- Microwave Irradiation},
}
%0 Journal Article
%T Investigation into the Reaction of 2-Amino- 4,5-dimethylthiophene-3-carboxamide with Iso(and Isothio)cyanates under Microwave Irradiation
%A Abolghasem Davoodnia
%A Rahimizadeh, Mohammad
%A Hoda Atapour-Mashhad
%A Niloofar Tavakoli-Hoseini
%J Heteroatom Chemistry
%@ 1042-7163
%D 2009
