Title : ( An efficient regioselective synthesis of highly functionalized 3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidines via an isocyanide-based three-component reaction )
Authors: Abbas Ali Esmaeili , Mahdieh Zangouei , Ali Reza Fakhari , Azizollah Habibi ,
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Abstract
We present a novel, convenient, and efficient method for synthesizing polysubstituted 3-oxo-2,3-dihydro- 5H-[1,3]thiazolo[3,2-a]pyrimidines via a three-component reaction. The zwitterions generated from the reaction of isocyanides and dialkyl acetylenedicarboxylates react with 2-imino-1,3-thiazolidin-4-one to produce the title compounds in good yields.
Keywords
, 2-Imino-1, 3-thiazolidin-4-one Dialkyl acetylenedicarboxylates, Alkyl isocyanides Thiazolo[3, 2-a]pyrimidine
@article{paperid:1025915,
author = {Esmaeili, Abbas Ali and Mahdieh Zangouei and Ali Reza Fakhari and Azizollah Habibi},
title = {An efficient regioselective synthesis of highly functionalized 3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidines via an isocyanide-based three-component reaction},
journal = {Tetrahedron Letters},
year = {2012},
volume = {53},
number = {11},
month = {January},
issn = {0040-4039},
pages = {1351--1353},
numpages = {2},
keywords = {2-Imino-1;3-thiazolidin-4-one
Dialkyl acetylenedicarboxylates; Alkyl
isocyanides
Thiazolo[3;2-a]pyrimidine},
}
%0 Journal Article
%T An efficient regioselective synthesis of highly functionalized 3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidines via an isocyanide-based three-component reaction
%A Esmaeili, Abbas Ali
%A Mahdieh Zangouei
%A Ali Reza Fakhari
%A Azizollah Habibi
%J Tetrahedron Letters
%@ 0040-4039
%D 2012
