Synlett, ( ISI ), Volume (13), No (13), Year (2009-1) , Pages (2119-2122)

Title : ( One-Pot, Three-Component Chemoselective Reaction of Isoquinolines, Dialkyl Acetylenedicarboxylates, and α-Ketolactones: An Unexpected Participation of an Ester Carbonyl Group in the 1,4-Dipolar Cycloaddition Reaction )

Authors: Abbas Ali Esmaeili , Mohsen Nazer ,

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The reaction of benzofuran-2,3-dione derivatives with dialkyl acetylenedicarboxylates (DAAD) and isoquinoline results in a three-component 1,4-dipolar cycloaddition reaction in which the ester carbonyl group is incorporated into a two-atom assembly to give spiro[1,3]oxazino[2,3-a]isoquinoline derivatives in good yield. This reaction provides the first example of an ester carbonyl group participating in a 1,4-dipolar cycloaddition reaction.

Keywords

, benzofuran-2, 3-dione - dialkyl acetylenedicarboxylates - isoquinolines - spiro[1, 3]oxazino[2, 3-a]isoquinolines - multicomponent
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@article{paperid:1026123,
author = {Esmaeili, Abbas Ali and Mohsen Nazer},
title = {One-Pot, Three-Component Chemoselective Reaction of Isoquinolines, Dialkyl Acetylenedicarboxylates, and α-Ketolactones: An Unexpected Participation of an Ester Carbonyl Group in the 1,4-Dipolar Cycloaddition Reaction},
journal = {Synlett},
year = {2009},
volume = {13},
number = {13},
month = {January},
issn = {0936-5214},
pages = {2119--2122},
numpages = {3},
keywords = {benzofuran-2;3-dione - dialkyl acetylenedicarboxylates - isoquinolines - spiro[1;3]oxazino[2;3-a]isoquinolines - multicomponent reactions},
}

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%0 Journal Article
%T One-Pot, Three-Component Chemoselective Reaction of Isoquinolines, Dialkyl Acetylenedicarboxylates, and α-Ketolactones: An Unexpected Participation of an Ester Carbonyl Group in the 1,4-Dipolar Cycloaddition Reaction
%A Esmaeili, Abbas Ali
%A Mohsen Nazer
%J Synlett
%@ 0936-5214
%D 2009

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