Title : ( A novel and efficient synthesis of 3,3-disubstituted indol-2-ones via Passerini three-component reactions in the presence of 4 Å molecular sieves )
Authors: Abbas Ali Esmaeili , Saeid Amini-Ghalandarabad , Saeideh Jannati ,
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Abstract
The Passerini coupling of cyclohexylisocyanide with isatins and carboxylic acids in the presence of 4 Å molecular sieves is described. This process offers a highly efficient and atom-economic access to 3-acyloxy- 3-carboxamido-1,3-dihydro-2H-indol-2-ones in high to excellent yields.
Keywords
, Isatin Isocyanide Passerini coupling reaction Carboxylic acid 3, 3-Disubstituted indol-2-ones
@article{paperid:1031423,
author = {Esmaeili, Abbas Ali and Saeid Amini-Ghalandarabad and Saeideh Jannati},
title = {A novel and efficient synthesis of 3,3-disubstituted indol-2-ones via Passerini three-component reactions in the presence of 4 Å molecular sieves},
journal = {Tetrahedron Letters},
year = {2013},
volume = {54},
number = {1},
month = {January},
issn = {0040-4039},
pages = {406--408},
numpages = {2},
keywords = {Isatin
Isocyanide
Passerini coupling reaction
Carboxylic acid
3;3-Disubstituted indol-2-ones},
}
%0 Journal Article
%T A novel and efficient synthesis of 3,3-disubstituted indol-2-ones via Passerini three-component reactions in the presence of 4 Å molecular sieves
%A Esmaeili, Abbas Ali
%A Saeid Amini-Ghalandarabad
%A Saeideh Jannati
%J Tetrahedron Letters
%@ 0040-4039
%D 2013
