Background: Today, healthy organizations such as hospital have found out the importance of quality of work life (QWL) of their personnel. QWL direct to increase job satisfaction, improve the quality of services to patient of hospital, and create high performance. One of factors that impact QWL is mistake management culture (MMC) when contribute different organization aspects such as QWL and cover its needs and finally promote job performance. Material and Method: A questionnarie was designed with items involve five-item Likert-type scale items and it distribute samong a sample of 207 nurses of four hospitals that voluntarily participated in research plan in Mashhad city. Two hospitals were private and two hospitals were public. Result: There are significant relationships between MMC, QWL and performance. Conclusion: According to importance of enhancement of QWL and job performance in organizations such as hospital, broadcasting culture of mistake management plays positive role and promotes quality level of work life of employees. Therefore, we can improve job satisfaction by changing and manipulating QWL factors, and thus move toward the development of the organization.

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