The aims of the present study were to: 1) elucidate the probable relationships between selenium (Se) concentration with cardiac troponin I (cTnI) concentrations and also with the activities of CK, and AST. 2) Determination of diagnostic eficiency and likelihood ratios of cTnI in diagnosis of Se deficiency. Sampling was conducted from 201 lambs with the age of less than one year old. Eleven lambs were rule out from study due to various diseases. Lambs were divided into two groups based on serum Se concentration: deficient lambs with Se concentration of ≤ 50 μg/L (n= 36) and control lambs (n=154) with the Se concentration of higher values. The concentration of cTnI was significantly higher in deficient sheep than control was (p<0.05). There was significant negative correlation between cTnI and Se concentration. The results of Receiver Operative Curve (ROC) analysis to evaluate the diagnostic eficiency of cTnI, AST, and CK were suggested that, the area under the curve (AUC) for cTnI (0.641) was significantly higher than reference line. At selected cut-off value for cTnI (0.06 μg/L) the sensitivity and specificity of test were 50% and 73%, respectively. The likelihood ratios (LRs) at selected cut-off point were +LR = 1.85, and -LR = 0.69, for cTnI.

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