Journal of the Brazilian Chemical Society, ( ISI ), Volume (24), No (6), Year (2013-1) , Pages (895-903)

Title : ( Green and Selective Synthesis ofN-Substituted Amides using Water Soluble Porphyrazinato Copper(II) Catalyst )

Authors: sara sadat emam jomae ghodsinia , Batool Akhlaghinia , Elham Safaei , Hossein Eshghi ,
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Abstract

N,N’,N’’,N’’’-Tetramethyl tetra-2,3-pyridinoporphyrazinato copper(II) methyl sulfate ([Cu(2,3‑tmtppa)](MeSO4)4) efficiently catalyzed the direct conversion of nitriles to N-substituted amides. The one pot selective synthesis of the N-substituted amides from nitriles and primary amines was performed in refluxing H2O. The catalyst was recovered and reused at least four times, maintaining its efficiency.

Keywords

, [Cu(2, 3-tmtppa)](MeSO4)4, N-substituted amide, nitrile, amine