Title : ( Synthesis of novel highly fluorescent of triazolo pyrimido[4,5-d] pyrimidin-4(1H)-one derivatives )
Authors: manijeh mohadeszadeh , Mohammad Rahimizadeh , Hossein Eshghi , Mostafa Gholizadeh , Ali Shiri ,
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Abstract
The pyrimidine ring system undoubtedly belongs to the most important heterocycles in nature, as it represent the main structure of many biologically active compounds, including nucleosides and nucleotides.[1-3] This work deals with synthesis and study of a novel system of heterocyclic compounds with highly fluorescent properties. The reaction starts by the synthesis of 6-amino 5-cyano 2-thiomethyl pyrimidine (1) as precursor. Dimorth rearangement on Compound (1) obtainded Compound (2) which was treated with hydrazine hydrate in ethanol and orthoesters in acetic acid, respectively, gave quantitatively the desired triazolo pyrimido pyrimidine (3). These novel synthesized heterocyclic system derivatives are highly fluorescent and can be used as marker in proteins.
Keywords
, highly fluorescent- triazolo pyrimido[4, 5-d] pyrimidin-4(1H)-one
@inproceedings{paperid:1036047,
author = {Mohadeszadeh, Manijeh and Rahimizadeh, Mohammad and Eshghi, Hossein and Gholizadeh, Mostafa and Shiri, Ali},
title = {Synthesis of novel highly fluorescent of triazolo pyrimido[4,5-d] pyrimidin-4(1H)-one derivatives},
booktitle = {16th Iranian Chemistry Congress},
year = {2013},
location = {یزد, IRAN},
keywords = {highly fluorescent- triazolo pyrimido[4;5-d] pyrimidin-4(1H)-one},
}
%0 Conference Proceedings
%T Synthesis of novel highly fluorescent of triazolo pyrimido[4,5-d] pyrimidin-4(1H)-one derivatives
%A Mohadeszadeh, Manijeh
%A Rahimizadeh, Mohammad
%A Eshghi, Hossein
%A Gholizadeh, Mostafa
%A Shiri, Ali
%J 16th Iranian Chemistry Congress
%D 2013
