21st International Iranian Congress of Physiology & Pharmacology , 2013-08-23

Title : ( Effet of Resveratrol in the improvement of mice testes abnormalities induced by Cisplatin )

Authors: sima jahanbakhshi , Nasser Mahdavi SHahri , Masoud Fereidoni , Morteza Behnam Rassouli ,

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Abstract

Introduction: Cisplatin is widely used in treatment of many tumors. Cisplatin is cytotoxic and apoptogenic in non-tumour cells and the formation of reactive oxygen species appears to be responsible for these toxicities. Resveratrol (RES) is a powerful antioxidant, that found in many plants, used recently in the treatment of infertility. The aim of this study is to evaluate the protective effect of resveratrol on cisplatin- induced testes damage in adult mice. ...

Keywords

, cisplatin, infertility, resveratrol, seminiferous epithelia, spermatogenesis