Research on Chemical Intermediates, ( ISI ), Volume (41), No (6), Year (2015-6) , Pages (3649-3658)

Title : ( PPh3-catalyzed Mannich reaction: a facile one-pot synthesis of b-amino carbonyl compounds under solvent-free conditions at room temperature )

Authors: javad abedini torghabeh , Hossein Eshghi , Mehdi Bakavoli , Mohammad Rahimizadeh ,

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PPh3 was used as an efficient catalyst for the one-pot three-component Mannich reactions of acetophenone with different aromatic amines and aromatic aldehydes under solvent-free conditions at room temperature. This method provides a novel and improved method for preparing b-amino carbonyl compounds in the absence of acidic catalyst in excellent yield. Little catalyst loading, easy accessibility of the catalyst, mild conditions, and simple work-up procedure are the main features of this protocol.

Keywords

, Mannich reaction,  One-pot,  Triphenylphosphine,  Solvent free,  b-Amino
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@article{paperid:1037916,
author = {Abedini Torghabeh, Javad and Eshghi, Hossein and Bakavoli, Mehdi and Rahimizadeh, Mohammad},
title = {PPh3-catalyzed Mannich reaction: a facile one-pot synthesis of b-amino carbonyl compounds under solvent-free conditions at room temperature},
journal = {Research on Chemical Intermediates},
year = {2015},
volume = {41},
number = {6},
month = {June},
issn = {0922-6168},
pages = {3649--3658},
numpages = {9},
keywords = {Mannich reaction;  One-pot;  Triphenylphosphine;  Solvent free;  b-Amino carbonyl},
}

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%0 Journal Article
%T PPh3-catalyzed Mannich reaction: a facile one-pot synthesis of b-amino carbonyl compounds under solvent-free conditions at room temperature
%A Abedini Torghabeh, Javad
%A Eshghi, Hossein
%A Bakavoli, Mehdi
%A Rahimizadeh, Mohammad
%J Research on Chemical Intermediates
%@ 0922-6168
%D 2015

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