Title : ( A new approach for C-substitution of 5-bromo-2,4-dichloro-6-methyl pyrimidine )
Authors: negin noorolahian , Ali Shiri , Mohammad Rahimizadeh ,
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Abstract
Heterocyclic compounds are present in a lot of bioactive compounds like DNA and RNA as pyrimidines and purines heterocyclic ring system. The biological significance of pyrimidine derivatives and structural similarities of these compounds with bioactive ones gave a prosperous scope to these compounds [14]. In this study, initially, 5bromo2,4dichloro6methyl pyrimidine (1) was synthesized according to our previous procedure [5]. The treatment of this compound with aqueous solution of NaOH gave quantitatively the novel an unexpected heterocyclic compound (2) which its structure was confirmed by its spectral and micro analytical data. The reaction of various secondary amines with this compound was also evaluated.
Keywords
, C-substitution - 5-bromo-2, 4-dichloro-6-methyl pyrimidine
@inproceedings{paperid:1040781,
author = {Noorolahian, Negin and Shiri, Ali and Rahimizadeh, Mohammad},
title = {A new approach for C-substitution of 5-bromo-2,4-dichloro-6-methyl pyrimidine},
booktitle = {21st Iranian Seminar of Organic Chemistry},
year = {2014},
location = {ایلام, IRAN},
keywords = {C-substitution - 5-bromo-2;4-dichloro-6-methyl pyrimidine},
}
%0 Conference Proceedings
%T A new approach for C-substitution of 5-bromo-2,4-dichloro-6-methyl pyrimidine
%A Noorolahian, Negin
%A Shiri, Ali
%A Rahimizadeh, Mohammad
%J 21st Iranian Seminar of Organic Chemistry
%D 2014
