BMC Structural Biology, Volume (14), No (18), Year (2014-7) , Pages (1-9)
Title : ( A simple method for finding a protein’s ligand-binding pockets )
Authors: Seyed Majid Saberi Fathi , Jack A Tuszynski ,Access to full-text not allowed by authors
Abstract
This paper provides a simple and rapid method for a protein-clustering strategy. The basic idea implemented here is to use computational geometry methods to predict and characterize ligand-binding pockets of a given protein structure. In addition to geometrical characteristics of the protein structure, we consider some simple biochemical properties that help recognize the best candidates for pockets in a protein’s active site.