BMC Structural Biology, Volume (14), No (18), Year (2014-7) , Pages (1-9)

Title : ( A simple method for finding a protein’s ligand-binding pockets )

Authors: Seyed Majid Saberi Fathi , Jack A Tuszynski ,

Access to full-text not allowed by authors

Citation: BibTeX | EndNote

Abstract

This paper provides a simple and rapid method for a protein-clustering strategy. The basic idea implemented here is to use computational geometry methods to predict and characterize ligand-binding pockets of a given protein structure. In addition to geometrical characteristics of the protein structure, we consider some simple biochemical properties that help recognize the best candidates for pockets in a protein’s active site.

Keywords

, Protein structure, Ligand-binding pockets, Computational methods