22nd Iranian Seminar of Organic Chemistry , 2014-08-19

Title : ( An EfficientSynthesis of New Derivatives of Pyrazolo[3,4-c]pyridazine )

Authors: ayla hazrathoseyni , Seyed Mohammad Seyedi , Hossein Eshghi , Ali Shiri ,

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1 The physicochemical and pharmacological properties of pyrazolo[3,4-c]pyridazine on the treatment of neuropathic pain[1] and anti-inflammatory activities[2]have been reported. Inhibitory activities ofseveral derivatives of this system on Cyclin-Dependent Kinases, HIV-1 Reverse Transcriptase and p38a mitogen-activated protein kinase[3] is determined.Hence, in this study wereport an efficient synthesis of new derivatives of 1-(4,7-diphenyl-4,7-dihydro-1Hpyrazolo[3,4-c]pyridazin-5-yl)ethanone that have been obtained by a very simple and straight forwardheterocyclization.The structures of all the synthesized products have been elucidated thoroughlybyelementalanalysis and spectral data.

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@inproceedings{paperid:1042734,
author = {Hazrathoseyni, Ayla and Seyedi, Seyed Mohammad and Eshghi, Hossein and Shiri, Ali},
title = {An EfficientSynthesis of New Derivatives of Pyrazolo[3,4-c]pyridazine},
booktitle = {22nd Iranian Seminar of Organic Chemistry},
year = {2014},
location = {تبریز, IRAN},
keywords = {“Synthesis”;“Heterocycle”;“Heterocyclization”;“Pyrazolo[3;4-c]pyridazine”},
}

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%0 Conference Proceedings
%T An EfficientSynthesis of New Derivatives of Pyrazolo[3,4-c]pyridazine
%A Hazrathoseyni, Ayla
%A Seyedi, Seyed Mohammad
%A Eshghi, Hossein
%A Shiri, Ali
%J 22nd Iranian Seminar of Organic Chemistry
%D 2014

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