Background & Objectives: This study aimed to compare the quality of anesthesia and recovery time of isoflurane and propofol in domestic pigeons.Procedures: Twenty pigeons (Columba Livia), weighing 302.5±37.95g (Mean ± SD) randomly allocated into two groups of ten. One group anesthetized by isoflurane (Iso-group) and anesthesia lasted for 30 minutes and another group, received 14 mg/kg of propofol (1%) was injected at constant rate (CRI) through basilica (wing) vein catheter to induce anesthesia (Pro-group). 1.33 mg/kg per min of propofol was infused to keep pigeons anesthetized for 30 minutes using an injection pump. Temperature, heart rate, respiratory rate and percentage of oxygen saturation of hemoglobin (SpO2%) were recorded in all three phases including; before induction of anesthesia, during anesthesia at minutes 1, 3, 5, 10, 15, 20, 25 and 30, and after recovery time in both groups.Results: Anesthesia caused significant effects on respiratory rate, heart rate and SpO2% (P≤0.05). Recovery times in both groups were significantly different (longer in propofol group). Conclusion: Our findings revealed that the pigeons anesthetized with isoflurane, have a soft and fast anesthesia but the pigeons were anesthetized with propofol, had a difficult induction that was not uniform for all pigeons. Isoflurane showed it is safer than propofol to anesthetize pigeons.

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