Physical Chemistry Research, Volume (2), No (2), Year (2014-9) , Pages (260-269)

Title : ( Antibacterial Activity of Short-Chained 1-Alkyl-3-methylimidazolium Bis(trifluoromethylsulfonyl) Imide Ionic Liquids )

Authors: Razieh Jalal , Elaheh Kafshdare Goharshadi , S. H . Sajjadi , Paul Nancarrowe ,

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The antibacterial activity of a series of ionic liquids containing short-chained 1-alkyl-3-methylimidazolium cations ([Cnmim+]; n = 2, 4,6 and 8) and bis (trifluoromethylsulfonyl) imide anion ([Tf2N]) against E. coli and B. subtilis was measured, for the first time. All ILs used in this work were synthesized and analyzed by Fourier transform infrared (FT-IR) spectroscopy, NMR, and Karl-Fischer titration. Antimicrobial activity was determined by the tube dilution method. The ILs investigated showed antibacterial activity against E. coli and B. subtilis. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) were in the ranges of 0.041-6.39 mM and 0.67-12.78 mM, respectively. The antibacterial activity for ionic liquids with longer alkyl chain (n ≥ 4) increased with increasing alkyl chain length. The highest inhibition against E. coli was found for [C8mim][Tf2N] (MIC = 0.041 mM and MBC = 0.67 mM). The mechanism of action of these ionic liquids was bacteriostatic.

Keywords

, Ionic liquid, Antibacterial activity, Imidazolium salts, Bis (trifluoromethylsulfonyl)
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@article{paperid:1045231,
author = {Jalal, Razieh and Kafshdare Goharshadi, Elaheh and S. H . Sajjadi and Paul Nancarrowe},
title = {Antibacterial Activity of Short-Chained 1-Alkyl-3-methylimidazolium Bis(trifluoromethylsulfonyl) Imide Ionic Liquids},
journal = {Physical Chemistry Research},
year = {2014},
volume = {2},
number = {2},
month = {September},
issn = {2322-5521},
pages = {260--269},
numpages = {9},
keywords = {Ionic liquid; Antibacterial activity; Imidazolium salts; Bis (trifluoromethylsulfonyl) imide},
}

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%0 Journal Article
%T Antibacterial Activity of Short-Chained 1-Alkyl-3-methylimidazolium Bis(trifluoromethylsulfonyl) Imide Ionic Liquids
%A Jalal, Razieh
%A Kafshdare Goharshadi, Elaheh
%A S. H . Sajjadi
%A Paul Nancarrowe
%J Physical Chemistry Research
%@ 2322-5521
%D 2014

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