Title : ( Different steps of sexual development are differentially regulated by the Sec8p and Exo70p exocyst subunits )
Authors: Mirza Mohammad Reza Sharifmoghadam , Nagore de Leon , Marta Hoya , Mariıa-Angeles Curto , Marıa-Henar Valdivieso ,
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Abstract
In this paper we show that in Schizosaccharomyces pombe, mating-specific cell adhesion is dependent on the exocyst subunit Sec8p, but independent of the exocyst subunit Exo70p. In the absence of Exo70p, the forespore membrane does not develop properly and the leading edge protein Meu14p is abnormally distributed. Additionally, the spindle pole body is aberrant in a significant number of exo70D asci. In both the sec8-1 and the exo70D mutants, the development of the spore cell wall is impaired. These results show that different steps of sexual development are differentially regulated by the exocyst and suggest the existence of exocyst subcomplexes with distinct roles in mating.
Keywords
yeast; sexual development; mating; sporulation; exocyst; protein trafficking
@article{paperid:1045784,
author = {Sharifmoghadam, Mirza Mohammad Reza and Nagore De Leon and Marta Hoya and Mariıa-Angeles Curto and Marıa-Henar Valdivieso},
title = {Different steps of sexual development are differentially regulated by the Sec8p and Exo70p exocyst subunits},
journal = {FEMS Microbiology Letters},
year = {2010},
volume = {305},
number = {1},
month = {February},
issn = {0378-1097},
pages = {71--80},
numpages = {9},
keywords = {yeast; sexual development; mating; sporulation; exocyst; protein trafficking},
}
%0 Journal Article
%T Different steps of sexual development are differentially regulated by the Sec8p and Exo70p exocyst subunits
%A Sharifmoghadam, Mirza Mohammad Reza
%A Nagore De Leon
%A Marta Hoya
%A Mariıa-Angeles Curto
%A Marıa-Henar Valdivieso
%J FEMS Microbiology Letters
%@ 0378-1097
%D 2010
