Title : ( Synthesis of [1,2,4]triazolo[4′′,3′′:1′,6′]pyrimido[4′,5′:3,4]pyridazino[1,6-d ] [1,2,4]triazine; a novel tetracyclic system )
Authors: ayla hazrathoseyni , Seyed Mohammad Seyedi , Ali Shiri , Hossein Eshghi ,
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Abstract
The condensation reaction of 6‑acetyl‑3‑amino‑5‑aryl‑2‑phenyl‑2,5‑dihydropyridazine‑4‑carbonitrile with triethyl orthoformate and then with hydrazine hydrate to obtain the new fused bicyclic 4‑aryl‑5‑hydrazinyl‑3‑(1‑hydrazonoethyl)‑1‑phenyl‑1,4‑ dihydropyrimido[4,5‑c]pyridazines via the Dimroth rearrangement is reported. Further cyclisation was achieved by the treatment of latter compounds with triethyl orthoformate to afford several derivatives of a novel tetracyclic fused system [1,2,4] triazolo[4′′,3′′:1′,6′]pyrimido[4′,5′:3,4]pyridazino[1,6‑d ][1,2,4]triazine.
Keywords
, triazolopyrimidines, pyrimidopyridazines, pyridazinotriazines, triazolopyrimidopyridazinotriazine
@article{paperid:1047355,
author = {Hazrathoseyni, Ayla and Seyedi, Seyed Mohammad and Shiri, Ali and Eshghi, Hossein},
title = {Synthesis of [1,2,4]triazolo[4′′,3′′:1′,6′]pyrimido[4′,5′:3,4]pyridazino[1,6-d ] [1,2,4]triazine; a novel tetracyclic system},
journal = {Journal of Chemical Research},
year = {2015},
volume = {39},
number = {3},
month = {March},
issn = {1747-5198},
pages = {148--153},
numpages = {5},
keywords = {triazolopyrimidines; pyrimidopyridazines; pyridazinotriazines; triazolopyrimidopyridazinotriazine},
}
%0 Journal Article
%T Synthesis of [1,2,4]triazolo[4′′,3′′:1′,6′]pyrimido[4′,5′:3,4]pyridazino[1,6-d ] [1,2,4]triazine; a novel tetracyclic system
%A Hazrathoseyni, Ayla
%A Seyedi, Seyed Mohammad
%A Shiri, Ali
%A Eshghi, Hossein
%J Journal of Chemical Research
%@ 1747-5198
%D 2015
