Journal of Chemical Research, ( ISI ), Volume (39), No (3), Year (2015-3) , Pages (174-176)

Title : ( An alternative approach to the synthesis of new pyrimido[5′,4′:5,6][1,4] thiazino[2,3-b]quinoxaline derivatives )

Authors: Mehdi Bakavoli , Hossein Eshghi , hamid azizolahy , satar saberi , marzieh akbarzadeh ,

Access to full-text not allowed by authors

Citation: BibTeX | EndNote

An alternative approach to the synthesis of a series of new pyrimido[5′,4′:5,6][1,4]thiazino[2,3-b]quinoxaline derivatives is described. Reaction of 5‑bromo-2,4-dichloro-6-methylpyrimidine and 3‑aminoquinoxaline-2-thiol leads to the key intermediate 3-[(5-bromo-2-chloro-6-methylpyrimidin-4-yl)thio]quinoxalin-2-amine. This intermediate can be transformed into the title ring systems by subsequent treatment either with secondary amines followed by intramolecular cyclisation or initial intramolecular cyclisation with subsequent reaction with secondary amines.

Keywords

, synthesis of pyrimido[5′, 4′:5, 6][1, 4]thiazine, quinoxaline, secondary amines, intramolecular cyclisation, intramolecular
برای دانلود از شناسه و رمز عبور پرتال پویا استفاده کنید.

@article{paperid:1047700,
author = {Bakavoli, Mehdi and Eshghi, Hossein and Azizolahy, Hamid and Saberi, Satar and Akbarzadeh, Marzieh},
title = {An alternative approach to the synthesis of new pyrimido[5′,4′:5,6][1,4] thiazino[2,3-b]quinoxaline derivatives},
journal = {Journal of Chemical Research},
year = {2015},
volume = {39},
number = {3},
month = {March},
issn = {1747-5198},
pages = {174--176},
numpages = {2},
keywords = {synthesis of pyrimido[5′;4′:5;6][1;4]thiazine; quinoxaline; secondary amines; intramolecular cyclisation; intramolecular cyclisation},
}

[Download]

%0 Journal Article
%T An alternative approach to the synthesis of new pyrimido[5′,4′:5,6][1,4] thiazino[2,3-b]quinoxaline derivatives
%A Bakavoli, Mehdi
%A Eshghi, Hossein
%A Azizolahy, Hamid
%A Saberi, Satar
%A Akbarzadeh, Marzieh
%J Journal of Chemical Research
%@ 1747-5198
%D 2015

[Download]