Journal of Heterocyclic Chemistry, ( ISI ), Volume (53), No (3), Year (2016-5) , Pages (832-839)

Title : ( Synthesis of Oxazolo[5,4-d][1,2,4]triazolo[4,3-a]pyrimidines as a New Class of Heterocyclic Compounds )

Authors: marzieh akbarzadeh , Mehdi Bakavoli , Hossein Eshghi , Ali Shiri ,

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Several new derivatives of oxazolo[5,4-d]pyrimidine (3a–h) have been synthesized through the reaction of 2,4-dichloro-6-methyl-5-nitropyrimidine (2) with aryl carboxylic acids in refluxing POCl. Further treatment of compounds (3a–h) with hydrazine hydrate gave the hydrazine derivatives (4a–h) that were subsequently cyclized into a novel heterocyclic system, oxazolo[5,4-d][1,2,4]triazolo[4,3-a]pyrimidine (5a–p) and (7a–d) on treatment with triethylorthoesters or carbondisulfide and alkylhalides, respectively.

Keywords

, Oxazolo[5, 4-d][1, 2, 4]triazolo[4, 3-a]pyrimidines- Heterocyclic
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@article{paperid:1048354,
author = {Akbarzadeh, Marzieh and Bakavoli, Mehdi and Eshghi, Hossein and Shiri, Ali},
title = {Synthesis of Oxazolo[5,4-d][1,2,4]triazolo[4,3-a]pyrimidines as a New Class of Heterocyclic Compounds},
journal = {Journal of Heterocyclic Chemistry},
year = {2016},
volume = {53},
number = {3},
month = {May},
issn = {0022-152X},
pages = {832--839},
numpages = {7},
keywords = {Oxazolo[5;4-d][1;2;4]triazolo[4;3-a]pyrimidines- Heterocyclic Compounds},
}

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%0 Journal Article
%T Synthesis of Oxazolo[5,4-d][1,2,4]triazolo[4,3-a]pyrimidines as a New Class of Heterocyclic Compounds
%A Akbarzadeh, Marzieh
%A Bakavoli, Mehdi
%A Eshghi, Hossein
%A Shiri, Ali
%J Journal of Heterocyclic Chemistry
%@ 0022-152X
%D 2016

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