Journal of Heterocyclic Chemistry, ( ISI ), Volume (53), No (4), Year (2016-7) , Pages (1231-1235)

Title : ( A Straightforward Approach for the Synthesis of Novel Derivatives of Benzo [b] pyrazolo [5,1: 2,3] pyrimido [4, 5-e] [1,4] thiazine )

Authors: seddigheh sheikhi mohammareh , Ali Shiri , Mehdi Bakavoli , Joel Mague ,

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Abstract

Several derivatives of the novel benzo[b]pyrazolo[5′,1′:2,3]pyrimido[4,5-e][1,4]thiazine ring system have been synthesized through the one-pot cyclocondensation of 6-bromo-7-chloro-2-(ethylthio)5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile (4) with o-aminothiophenol in the presence of Et3N in CH3CN. The true regio isomer (5) was also determined by X-ray crystallographic analysis. The N-alkylation of the synthesized compound (5) was also accomplished.

Keywords

, Benzo[b]pyrazolo[5′, 1′:2, 3]pyrimido[4, 5-e][1, 4]thiazine
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@article{paperid:1048864,
author = {Sheikhi Mohammareh, Seddigheh and Shiri, Ali and Bakavoli, Mehdi and Joel Mague},
title = {A Straightforward Approach for the Synthesis of Novel Derivatives of Benzo [b] pyrazolo [5,1: 2,3] pyrimido [4, 5-e] [1,4] thiazine},
journal = {Journal of Heterocyclic Chemistry},
year = {2016},
volume = {53},
number = {4},
month = {July},
issn = {0022-152X},
pages = {1231--1235},
numpages = {4},
keywords = {Benzo[b]pyrazolo[5′;1′:2;3]pyrimido[4;5-e][1;4]thiazine},
}

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%0 Journal Article
%T A Straightforward Approach for the Synthesis of Novel Derivatives of Benzo [b] pyrazolo [5,1: 2,3] pyrimido [4, 5-e] [1,4] thiazine
%A Sheikhi Mohammareh, Seddigheh
%A Shiri, Ali
%A Bakavoli, Mehdi
%A Joel Mague
%J Journal of Heterocyclic Chemistry
%@ 0022-152X
%D 2016

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