Title : ( A One-Pot, Fast, and Efficient Amidation of Carboxylic Acids, α-Amino Acids and Sulfonic Acids Using PPh3/N-chlorobenzotriazole System )
Authors: Hamed Rouhi Sadabad , Batool Akhlaghinia ,
Full TextAbstract
Triphenylphosphine (PPh3)/N-chlorobenzotriazole (NCBT), and amine (primary and secondary aliphatic amines and also substituted anilines) in CH2Cl2 efficiently converted carboxylic acids, α-amino acids, and sulfonic acids to the corresponding amides and sulfonamides at room temperature. Good to excellent yields, inexpensive, and fast reaction conditions are the important features of this procedure.
Keywords
, Amidation; carboxylic acid; amino acid; sulfonic acid; triphenylphosphine; Nchlorobenzotriazole; one, pot synthesis
@article{paperid:1049399,
author = {Rouhi Sadabad, Hamed and Akhlaghinia, Batool},
title = {A One-Pot, Fast, and Efficient Amidation of Carboxylic Acids, α-Amino Acids and Sulfonic Acids Using PPh3/N-chlorobenzotriazole System},
journal = {Phosphorus, Sulfur, and Silicon and the Related Elements},
year = {2015},
volume = {190},
number = {10},
month = {October},
issn = {1042-6507},
pages = {1703--1714},
numpages = {11},
keywords = {Amidation; carboxylic acid; amino acid; sulfonic acid; triphenylphosphine; Nchlorobenzotriazole;
one-pot synthesis},
}
%0 Journal Article
%T A One-Pot, Fast, and Efficient Amidation of Carboxylic Acids, α-Amino Acids and Sulfonic Acids Using PPh3/N-chlorobenzotriazole System
%A Rouhi Sadabad, Hamed
%A Akhlaghinia, Batool
%J Phosphorus, Sulfur, and Silicon and the Related Elements
%@ 1042-6507
%D 2015
