Title : ( Efficient synthesis of novel pyrano[2,3- d ]pyrido[1,2- a ]pyrimidine derivatives via isocyanide-based three-component reactions )
Authors: Abbas Ali Esmaeili , fariba salehan , Azizollah Habibi , Ali Reza Fakhari ,
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Abstract
The synthesis of novel tricyclic fused pyrano[2,3-d]pyrido[1,2-a]pyrimidines containing both biologically active pyridopyrimidine and pyranopyrimidine scaffolds, via the reaction of 2H-pyrido[1,2-a]pyrimidine- 2,4(3H)-dione, isocyanides, and dialkylacetylenedicarboxylates are reported. The products were obtained in good to excellent yields over short reaction times and with a simple work-up procedure.
Keywords
, Multi-component reaction, Pyranopyridopyrimidine, Acetylenic esters, Alkyl isocyanide, One-pot synthesis
@article{paperid:1053153,
author = {Esmaeili, Abbas Ali and Salehan, Fariba and Azizollah Habibi and Ali Reza Fakhari},
title = {Efficient synthesis of novel pyrano[2,3- d ]pyrido[1,2- a ]pyrimidine derivatives via isocyanide-based three-component reactions},
journal = {Tetrahedron Letters},
year = {2016},
volume = {57},
number = {1},
month = {January},
issn = {0040-4039},
pages = {100--102},
numpages = {2},
keywords = {Multi-component reaction; Pyranopyridopyrimidine; Acetylenic esters; Alkyl isocyanide; One-pot synthesis},
}
%0 Journal Article
%T Efficient synthesis of novel pyrano[2,3- d ]pyrido[1,2- a ]pyrimidine derivatives via isocyanide-based three-component reactions
%A Esmaeili, Abbas Ali
%A Salehan, Fariba
%A Azizollah Habibi
%A Ali Reza Fakhari
%J Tetrahedron Letters
%@ 0040-4039
%D 2016
