There are few extensive studies about biochemical profiles of caprine anaplasmosis caused by Anaplasma ovis. For detection of A. ovis and its effect on serum biochemical parameters in goats of north and northeast Iran, blood samples were collected from 84 goats of different ages and of both sexes from ten suspected herds to anaplasmosis. Forty-seven out of 84 samples were positive (infected), and 37 samples were negative (uninfected) for A. ovis by PCR method. Biochemical analysis of infected goats indicated a significant (P < 0.05) elevation of serum aspartate aminotransferase, γ-glutamyl transferase, urea, creatinine, total bilirubin, and direct bilirubin, in addition to a nonsignificant (P > 0.05) increase of total protein, albumin, and triglyceride, when compared to the uninfected goats. The cholesterol concentration in the infected goats was lower than that in the uninfected goats, but this difference was not statistically significant (P > 0.05). The result of this study indicated that A. ovis infection in goats could be associated with marked alterations in serum biochemical parameters which could be helpful in the diagnosis of caprine anaplasmosis.

Keywords