Cell Biology International, ( ISI ), Volume (40), No (9), Year (2016-9) , Pages (955-967)

Title : ( CXCR4 and CCR7: Two eligible targets in targeted cancer therapy )

Authors: Mohammad Amir Mishan , Naghmeh Ahmadiankia , Ahmad Reza Bahrami ,

Citation: BibTeX | EndNote

Cancer is one of the most common cause of death in the world with high negative emotional, economic, and social impacts. Conventional therapeutic methods, including chemotherapy and radiotherapy, have not proven satisfactory and relapse is common in most cases. Recent studies have focused on targeted therapy with more precise identification and targeted attacks to the cancer cells. For this purpose, chemokine receptors are proper targets and among them, CXCR4 and CCR7, with a crucial role in cancer metastasis, are being considered as desired candidates for investigation. In this review paper, the most important experimental results are highlighted on the potential targeted therapies based on CXCR4 and CCR7 chemokine receptors.

Keywords

CCR7; chemokine receptor; CXCR4; targeted cancer
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@article{paperid:1060235,
author = {Mishan, Mohammad Amir and Naghmeh Ahmadiankia and Bahrami, Ahmad Reza},
title = {CXCR4 and CCR7: Two eligible targets in targeted cancer therapy},
journal = {Cell Biology International},
year = {2016},
volume = {40},
number = {9},
month = {September},
issn = {1065-6995},
pages = {955--967},
numpages = {12},
keywords = {CCR7; chemokine receptor; CXCR4; targeted cancer therapy},
}

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%0 Journal Article
%T CXCR4 and CCR7: Two eligible targets in targeted cancer therapy
%A Mishan, Mohammad Amir
%A Naghmeh Ahmadiankia
%A Bahrami, Ahmad Reza
%J Cell Biology International
%@ 1065-6995
%D 2016

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