Journal of the Iranian Chemical Society, ( ISI ), Volume (14), No (12), Year (2017-10) , Pages (2591-2597)

Title : ( Rapid, Green, And Catalyst‑Free One‑ Pot Three‑Component Syntheses Of 5‑ substituted 1H‑tetrazoles In Magnetized Water )

Authors: M. Bakherad , R. Doosti , A. Keivanloo , Mostafa Gholizadeh , Kh. Jadidi ,
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Abstract

Abstract The catalyst-free multi-component reactions of aldehydes, malononitrile, and sodium azide at a relatively low temperature in magnetized water provided 5-substituted 1H-tetrazoles in high-to-excellent yields. This method ofers the advantages of short reaction times, low costs, quantitative reaction yields, simple work-up, green, and no need for any organic solvent.

Keywords

, Magnetized water · Catalyst, free · Green method · 5, Substituted 1H, tetrazoles