Title : ( Synthesis of a novel fused tricyclic heterocycle, pyrimido[5,4- e ][1,4]thiazepine, and its derivatives )
Authors: tahmineh bazazan noghani , Mehdi Bakavoli , Mohammad Rahimizadeh , Hossein Eshghi , M. Nikpour ,
دانلود فایل برای اعضای دانشگاهAccess to full-text not allowed by authors
Abstract
Sequential treatment of 5-bromo-2,4-dichloro- 6-(chloromethyl)pyrimidine with 2-aminothiophenol and secondary amines afforded a series of 2-[(5-bromo- 2-chloro-6-aminopyrimidin-4-yl)methylthio]aniline derivatives. Reaction of the latter compounds with secondary amines in ethanol gave a family of new 5,7-diamino- 5,11-dihydropyrimido[5,4- e ][1,4]benzothiazepines.
Keywords
, [5, 4- e ][1, 4]benzothiazepines; nucleophilic substitution; secondary amines; 1, 4-thiazepine
@article{paperid:1065251,
author = {Bazazan Noghani, Tahmineh and Bakavoli, Mehdi and Rahimizadeh, Mohammad and Eshghi, Hossein and M. Nikpour},
title = {Synthesis of a novel fused tricyclic heterocycle, pyrimido[5,4- e ][1,4]thiazepine, and its derivatives},
journal = {Heterocyclic Communications},
year = {2013},
volume = {19},
number = {6},
month = {December},
issn = {0793-0283},
pages = {401--404},
numpages = {3},
keywords = {[5;4- e ][1;4]benzothiazepines; nucleophilic substitution;
secondary amines; 1;4-thiazepine},
}
%0 Journal Article
%T Synthesis of a novel fused tricyclic heterocycle, pyrimido[5,4- e ][1,4]thiazepine, and its derivatives
%A Bazazan Noghani, Tahmineh
%A Bakavoli, Mehdi
%A Rahimizadeh, Mohammad
%A Eshghi, Hossein
%A M. Nikpour
%J Heterocyclic Communications
%@ 0793-0283
%D 2013
