N-containing compounds have always remained a major source for therapeutic drugs and have received significant attention.1 Among them nitrogen-containing heterocycles such as tetrazoles have attracted considerable interest because of their wide range of applications in material sciences (including explosives and rocket propellants), synthetic organic chemistry as analytical reagents,2 and synthons for a variety of nitrogen containing heterocycles.3 Tetrazoles have been successfully used in coordination chemistry as ligands for many useful transformations,4 in medicinal chemistry as a more favorable pharmacokinetic profile and a metabolically stable surrogate for carboxylic acid functionalities. In this research 2-aminoethanesulfonic acid immobilized on epichlorohydrin functionalized Fe3O4@WO3 has been introduced as a novel and efficient magnetic nanocatalyst for appropriate and rapid synthesis of 1-Substituted-1H-1,2,3,4-tetrazoles. This new nanocatalyst was then characterized using FT-IR, XRD, TEM, EDS, TGA, FE-SEM, CHNS and VSM techniques.

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